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Updated: May 5, 2026

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线粒体能量状态控制在C.中AMPK介导的食行为. 伊莱根斯 (elegans) 是一个词

Anežka Vodičková1, Annika Müller-Eigner2, Chidozie N Okoye1

  • 1Department of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center, Rochester, NY, USA.

Science advances
|April 17, 2024
PubMed
概括

肠道中的线粒体质子运动力 (PMF) 表示食物的可用性. 它的减少触发了通过神经元AMP激活蛋白激酶 (AMPK) 的食行为.

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Mitochondrial protein import is powered by two distinct energy sources: ATP hydrolysis and electrochemical potential across the inner membrane. Newly synthesized precursors are bound by cytosolic chaperones of the Hsp70 family, which guide them to the import receptors on the mitochondrial surface. Utilizing the energy of ATP hydrolysis, Hsp70 chaperones transfer these precursors to the TOM receptors on the mitochondrial outer membrane.
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