儿科支气管病的放射性结果和与可逆性相关的因素
Dustin R Mills1,2,3, Ian B Masters1,4, Stephanie T Yerkovich4,5
1Department of Respiratory and Sleep Medicine and.
儿科支气管病变通常是可逆的,40%的儿童显示完全的X光学分辨率. 年龄较小,初始症状较轻,没有Pseudomonas aeruginosa感染预测更好的结果.
科学领域:
- 儿科肺病学 儿科肺病学
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
背景情况:
- 儿童的支气管切除症传统上被认为是不可逆转的.
- 最近的小型研究表明潜在的可逆性.
- 影响放射学分辨率的因素仍未确定.
研究的目的:
- 为了确定支气管切除症可逆性的程度在一个大的儿科队列.
- 确定与胸部高分辨率计算机断层扫描 (cHRCT) 放射分辨率相关的因素.
主要方法:
- 对142名重复cHRCT扫描的儿童 (2010-2021) 的回顾性分析.
- 排除标准:囊性纤维化,外科手术,引支气管切开,叶片化.
- 使用修改后的雷夫得分 (MRS) 进行评分;分辨率定义为随访时正常的支气管动脉比率cHRCT.
主要成果:
- 在40.1% (57/142) 观察到X光学分辨率,在39.4% (56/142) 观察到改善.
- 伪omonas aeruginosa (PsA) 感染与缺乏解决方案密切相关.
- 年轻的年龄,较低的MRS和较少的恶化预测PsA阴性患者的解决方案.
结论:
- 这一庞大的队列证实,在适当管理的情况下,支气管切除症在儿童中往往是可逆的.
- 年龄较小的儿童和初始cHRCT发现不那么严重的儿童更有可能达到解决.
- PsA感染显著降低了放射性可逆性的可能性.
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