这封信的附录: "标准和基于参考的条件平均值归算:监管机构和试验统计学家要注意!"
Marcel Wolbers1, Alessandro Noci1, Paul Delmar1
1Data & Statistical Sciences, Pharma Development, Roche, Basel, Switzerland.
Pharmaceutical statistics
|April 17, 2024
概括
条件平均值归算和多重归算对于基于参考的缺失数据是相似的. 条件平均值归算可以调整差异估计,为处理缺失数据提供灵活的方法.
科学领域:
- 统计 统计 统计 统计
- 生物统计学 生物统计学
- 缺失的数据分析
背景情况:
- 目前正在进行的关于基于参考的归算方法的差异估计的辩论,特别是"多重归算"与"条件平均归算",需要澄清.
- 这两种方法都有共同的基本假设,并产生可比的治疗效果估计,挑战了所提出的二分法.
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