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Updated: Jun 28, 2025

Accessing Valuable Ligand Supports for Transition Metals: A Modified, Intermediate Scale Preparation of 1,2,3,4,5-Pentamethylcyclopentadiene
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Accessing Valuable Ligand Supports for Transition Metals: A Modified, Intermediate Scale Preparation of 1,2,3,4,5-Pentamethylcyclopentadiene

Published on: March 20, 2017

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与螺旋胺连体的非共价相互作用使得催化C-H的有效激活成为可能

Yushu Jin1, Boobalan Ramadoss1, Sobi Asako2

  • 1RIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan.

Nature communications
|April 17, 2024
PubMed
概括

研究人员利用弱CH-π相互作用加速催化C-H激活. 这种新的方法利用螺旋胺连接体来识别基基质中的π电子,为有机合成中先进的催化剂设计铺平了道路.

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Radical reactions can occur either intermolecularly or intramolecularly. In an intermolecular radical reaction, a nucleophilic radical adds to an electrophilic alkene or vice versa. In such reactions, the radical and generally the alkene, which is also called the radical trap, are two different molecules. Additionally, for such intermolecular reactions to occur, the radical trap must be active, present in an excess concentration, and the radical starting material must have a weak...
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