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全球纵向应变是接受重症监护的新生儿左心室表现的信息指数

Enrico Petoello¹, Alice Iride Flore¹, Silvia Nogara¹

¹Neonatal Intensive Care Unit, University and Hospital Trust of Verona, P.le A. Stefani 1, 37126, Verona, Italy.

Scientific reports

|April 17, 2024

概括

全球纵向应变 (GLS) 在评估新生儿左心室功能方面提供了优越的准确性,与传统的心声回声学方法相比. 这种先进的技术显示出更大的诊断能力,对于严重疾病的新生儿的未补偿性休克.

科学领域:

新生儿心脏病学新生儿心脏病学
心声回声扫描 (Echocardiography) 是一种心声回声扫描.
儿科重症监护儿科重症监护

背景情况:

准确评估左心室功能对于新生儿在新生儿重症监护室 (NICU) 的新生儿至关重要.
传统的回声心脏学参数,如缩短分数 (SF),射出分数 (EF) 和S'在反映真正的心脏表现方面存在局限性.
全球纵向应变 (GLS) 是一种评估心肌变形的新兴技术.

研究的目的:

为了比较全球纵向应变 (GLS) 的准确性和一致性,与新生儿的传统心声谱测量进行比较.
评估GLS在诊断严重病重的新生儿中未补偿性休克时的诊断性能.
为了确定GLS与按体重 (iSV) 索引的中风体积的相关性.

主要方法:

对 155 名新生儿 (334 项研究) 的现实心声图进行了回顾性审查,这些新生儿被录入新生儿重症监护室.
从存储的心声回声图像下线计算GLS.
将GLS与SF,EF和S'进行比较,使用回归分析与iSV和ROC曲线分析进行关联,以诊断无补偿冲击. 科恩的卡帕被用于协议评估.

主要成果:

GLS与iSV有很强的关联 (R2=0.633,p<0.001),这解释了多变量模型 (73%) 中显著部分的差异.
与EF (AUC=0.757),S' (AUC=0.737) 和SF (AUC=0.606) 相比,GLS显示出对未补偿性休克的诊断能力优越 (AUC=0.956).
GLS与EF (κ=0.500) 呈现中度一致,与S' (κ=0.260) 和SF (κ=0.242) 呈现有限一致.

结论:

全球纵向应变 (GLS) 是对新生儿左心室表现的更有信息的指标,而不是传统的心声回声学参数.
GLS在诊断重病新生儿未补偿性休克时表现出卓越的准确性.
这些发现支持在床边扩大GLS的使用,以进行全面的新生儿心脏评估.

关键词:

心声回声扫描 (Echocardiography) 是一种心声回声扫描.全球纵向菌株全球纵向菌株婴儿,新生儿新生儿重症监护,新生儿重症监护左心室功能,左心室功能

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