使用机器学习的多种癌症早期检测血液测试可以检测缺乏USPSTF推的查的早期癌症
Janet Vittone1, David Gill2, Alex Goldsmith3
1Mayo Clinic, Rochester, Minnesota, USA.
NPJ precision oncology
|April 17, 2024
概括
针对多种癌症的早期检测 (MCED) 的血液检测显示出,目前的查指南未能识别出癌症的可能性. 这些测试可以检测个体的早期癌症,从而有可能改善治疗结果.
科学领域:
- 在瘤学瘤学.
- 基因组学就是基因组学.
- 翻译医学是一种翻译医学.
背景情况:
- 目前美国预防服务工作组 (USPSTF) 的指导方针侧重于单一癌症查.
- 基因组测序和机器学习的进步使新的诊断方法成为可能.
- 基于血液的多种癌症早期检测 (MCED) 测试正在出现,以补充现有的查方法.
研究的目的:
- 评估多种癌症早期检测 (MCED) 试验的实际实用性.
- 证明MCED测试在识别目前查指南未涵盖的癌症方面的潜力.
- 突出MCED测试在检测早期,可治愈的癌症方面的能力.
主要方法:
- 利用基于血液的MCED测试分析循环的无细胞DNA.
- 在多种瘤类型中查询共享的癌症信号.
- 报告了临床病例,其中MCED测试检测到癌症信号.
主要成果:
- 在三个人中,MCED测试确定了癌症信号.
- 这些人随后被诊断出患有卵巢,脏和头癌.
- 这些癌症目前缺乏USPSTF推的查协议.
结论:
- MCED测试显示了检测早期癌症的潜力.
- 这些测试可以在缺乏标准查建议的个体中识别癌症.
- MCED测试可以提高癌症检测率,并促进及时治疗.
更多相关视频
10:35A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction
Published on: April 5, 2018
10.3K
07:15Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
Published on: August 16, 2020
6.8K
相关概念视频
02:59Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
01:30Serum Laboratory Studies, Stool Test, Breath Test
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...