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基于NHANES的分析,分析了休时间的体力活动,血清中胆胺水平和牙周炎风险之间的相关性
Hua Fu1, Diya Zhang2, Yining Li3
1Shangyu people's Hospital, Shaoxing City, Zhejiang Province, 312300, China. crest0932@163.com.
BMC oral health
|April 17, 2024
概括
较低的体力活动和较高的血清丁氨酸水平显著增加牙周炎的风险. 结合起来,这些因素的风险比单独的风险更大,这凸显了运动和戒烟对口腔健康的重要性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 牙周病学 牙周病学
背景情况:
- 牙周炎是一种普遍存在的口腔疾病,具有重大公共卫生影响.
- 休时间的体力活动 (LTPA) 和血清中胆固醇水平 (吸烟暴露的生物标志物) 是牙周炎的潜在可修改的风险因素.
研究的目的:
- 在一般人群中调查LTPA,血清丁氨酸水平和牙周炎风险之间的关联.
- 分析LTPA和血清胆固醇水平对牙周炎风险的相互作用效应.
主要方法:
- 这是一项横截面研究,利用了国家健康和营养检查调查 (NHANES) 数据库 (2009-2014) 中9605名参与者的数据.
- 使用加权的单变量逻辑回归建模来分析关系和相互作用效应.
- 使用几率比率 (OR) 和95%置信区间 (95% CI) 来量化效应大小.
主要成果:
- 在LTPA < 750 MET × min/week (OR = 1.44,95% CI: 1.17-1.78) 的个体中观察到牙周炎的风险更高.
- 血清哥提宁水平≥0.05 ng/ml与牙周炎风险增加有关 (OR=1.99,95% CI:1.69-2.33).
- 低的LTPA和高的血清胆氨酸水平的综合作用显著增加了牙周炎风险 (OR = 2.48,95% CI: 1.88-3.27),具有显著的相互作用指标 (RERI = 0.90,API = 0.36).
结论:
- 休时间的体力活动强度与吸烟暴露相互作用 (通过血清中丁氨酸水平表示) 影响牙周炎风险.
- 针对普通人群的建议应强调增加LTPA和戒烟,以减轻牙周炎风险.
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