在患有乳病的女性患者中,生殖功能和怀孕结果
Shubham Prasad1, Priyanka Singh2, Alka Singh1
1Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.
Journal of gastroenterology and hepatology
|April 18, 2024
概括
生殖健康经常被忽视在乳病 (CeD). 这项研究发现,四分之三的患有CeD的女性经历了生殖功能和怀孕结果的问题.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 胃肠病学 胃肠病学
- 结核病研究 结核病研究
背景情况:
- 生殖功能障碍在患有乳病 (CeD) 的患者评估中经常没有得到解决.
- 本研究重点是对被诊断患有CeD的女性生殖功能的综合评估.
研究的目的:
- 研究和评估被诊断患有乳病的女性患者的生殖功能范围.
- 为了比较CeD妇女和年龄相匹配的健康对照之间的生殖健康参数.
主要方法:
- 在2020年至2021年期间进行了一项病例控制研究.
- 生殖功能 (月经,月经模式,生育能力,妊娠结果,更年期) 通过问卷对288名女性CeD患者 (>10年) 和586名对照患者进行了评估.
主要成果:
- 患有CeD的女性在初潮时表现出显著更高的年龄 (14.6岁对13.6岁) 和延迟初潮的患病率增加 (30.8%对11.4%).
- CeD患者报告了更多异常的月经模式 (39.7%vs25.8%),延迟受孕 (33.8%vs11.8%),以及更高的不孕率 (10.5%vs5.2%).
- 在CeD患者中,怀孕结果较差,堕胎率较高 (23.5%对12.8%),早产率较高 (16.3%对3.7%).
结论:
- 对生殖功能和怀孕结果的不良影响在绝大多数女性乳病患者中普遍存在.
- 这些发现凸显了将生殖健康评估纳入患有腹腔疾病的妇女日常护理的必要性.
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