在患有医院获得的COVID-19的患者中,进展至危急疾病的危险因素
Kyung-Eui Lee1, Jinwoo Lee2, Sang-Min Lee1,2
1Department of Critical Care Medicine, Seoul National University Hospital, Seoul, Korea.
The Korean journal of internal medicine
|April 18, 2024
概括
在医院获得的COVID-19患者有呼吸道或心血管疾病,免疫力受损状态或虚弱,患重症的风险更高. 早期识别和隔离对于更好的结果至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 流行病学 流行病学
背景情况:
- 在医院获得的2019年新冠肺炎疾病 (COVID-19) 中,进展至危急疾病的危险因素以前是未知的.
- 这项研究旨在确定这些风险因素及其对临床结果的影响.
研究的目的:
- 评估在医院获得的COVID-19中进展到严重疾病的发病率和风险因素.
- 确定这些风险因素对临床结果的影响.
主要方法:
- 这是一项对204名在2020年1月至2022年6月期间入院的医院获得的COVID-19患者的回顾性队列研究.
- 根据已识别的风险因素,患者被分为不同风险组.
- 多变量逻辑回归被用来分析进展至危急疾病的风险因素.
主要成果:
- 18.1%的患者 (共204人中37人) 进展至危急疾病.
- 预先存在的呼吸道疾病,心血管疾病,免疫受损状态,更高的顺序性器官衰竭评估 (SOFA) 评分和更高的临床脆弱性尺度是显著的危险因素.
- 增加风险组分层与更高的危险疾病进展率和28天死亡率相关.
结论:
- 预先存在的呼吸系统疾病,心血管疾病,免疫受损状态以及较高的SOFA和临床虚弱度评分是医院获得的COVID-19中严重疾病的关键风险因素.
- 优先考虑和隔离患有这些风险因素的患者对于及时治疗和改善结果至关重要,特别是在流行病期间.
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