单个D380氨基酸替代增加了对神经元细胞的肺聚氨酸细胞毒性

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Simona Serra1, Vittorio Iannotti1, Margherita Ferrante1

  • 1Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.

iScience
|April 18, 2024
PubMed
概括

单个氨基酸的变化在pneumolysin (PLY),一个毒素从Streptococcus pneumoniae,显著增加其神经毒性. 这种增强的PLY显著促进了细菌性脑膜炎的神经损伤.

关键词:
生物化学 生物化学生物科学 生物科学医学微生物学 医学微生物学微生物学 微生物学分子神经科学分子神经科学自然科学 自然科学神经科学是一个神经科学.

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