手持式接触式OCT和色底系统用于视网膜成像
Stefano Truzzi1,2, Fabrice Manns1,3, Jean-Marie Parel1,3,4
1Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Biomedical optics express
|April 18, 2024
概括
我们开发了一种新型的手持设备,用于同时进行视网膜光学连贯断层扫描 (OCT) 和 fundus 摄影. 这种综合系统简化了临床环境中的儿科患者的成像.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 生物医学工程 生物医学工程
背景情况:
- 对视网膜结构和眼底的同时成像对于全面的眼科检查至关重要.
- 现有系统通常需要多个设备,增加复杂性和空间需求.
- 儿童眼睛成像带来了独特的挑战,因为患者的运动和需要高效的程序.
研究的目的:
- 为了证明手持式,接触式系统的概念证明,集成光学连贯性断层扫描 (OCT) 和广场数字底部彩色摄影.
- 评估这种组合成像方法对儿科患者的可行性,特别是在手术室和新生儿重症监护室.
主要方法:
- 开发一个紧的,模块化的手持设备,将OCT和 fundus成像功能结合起来.
- 使用直接接触探头设计来增强稳定性和减少运动工件.
- 评估系统的性能,同时进行视网膜成像和 fundus 摄影.
主要成果:
- 成功证明了一种手持式系统的概念,该系统能够同时对OCT和 fundus进行成像.
- 由于探头接触和稳定的定位,运动工件的减少.
- 通过综合设计实现了简化对齐和扩展视野.
结论:
- 拟议的综合手持系统提供了一个可行的解决方案,用于同时进行OCT和 fundus成像.
- 这项技术在儿科眼科医生中具有潜在的应用,特别是在麻醉下检查期间和新生儿重症监护室.
- 紧的单一设备设计简化了成像工作流程,减少了设备需求.
相关概念视频
01:18Imaging Biological Samples with Optical Microscopy
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
01:26Phase Contrast and Differential Interference Contrast Microscopy
Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...