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单纤维探针用于生物组织的综合传感和成像:最近的发展和前景

Jiawen Li^1,2, Stephen C Warren-Smith^2,3, Robert A McLaughlin^2,4

¹School of Electrical and Mechanical Engineering, The University of Adelaide, South Australia, 5005, Australia.

Biomedical optics express

|April 18, 2024

概括

单纤维探头允许在深层组织中同时传感和成像,从而推进生物过程观察和疾病诊断. 未来的研究旨在克服提高临床应用的灵敏度和分辨率方面的挑战.

科学领域:

生物医学光学生物医学光学
医疗成像医学成像
生物感应是一种生物感应.

背景情况:

单纤维探头为复杂的生物过程提供了同位和同时的传感和成像能力.
这项技术对于调查复杂的生理现象和改善疾病诊断和监测至关重要.

研究的目的:

审查基于单一纤维的探针的最新进展,用于并发和同位的光传感和成像.
确定开发这些集成设备的挑战和未来的研究机会.

主要方法:

关于用于综合传感和成像的单纤维探针的最新研究的综述.
对当前灵敏度和分辨率的局限性进行分析.

主要成果:

在微型单纤维设备中成功地进行了集成传感和成像的初步演示.
确定阻碍提高绩效的关键挑战.

结论:

单纤维探针在现场生物观测和疾病管理方面具有重大潜力.
未来的研究应该集中在先进的光学设计,新材料和综合技术上,以提高设备的灵敏度和成像分辨率.

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