作为一种潜在的抗菌剂,Moringa oleifera可以对农场动物中致病性Clostridium perfringens分离物产生抗菌作用
Ghada A Ibrahim1, Khadijah A Altammar2
1Agriculture Research Center (ARC), Animal Health Research Institute (AHRI), Bacteriology Department, Ismailia Branch, Egypt.
Open veterinary journal
|April 18, 2024
概括
莫林加橄花在牲畜中表现出强大的抗菌作用,可以对菌产生强烈的抗菌作用,其效果优于一些抗生素. 建议进行进一步的研究,以探索其作为抗生素耐药性的天然替代品的使用.
科学领域:
- 兽医微生物学 兽医微生物学
- 植物化学 植物化学
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 杆菌 (Clostridium perfringens,简称CP) 是一种新兴的无氧病原体,在牲畜中引起严重感染.
- 了解CP的流行率和抗生素耐药性模式对于动物健康管理至关重要.
研究的目的:
- 评估Moringa oleifera对来自各种农场动物的Clostridium perfringens分离物的抗菌疗效.
- 为了比较Moringa oleifera与兽医中使用的商业抗生素的疗效.
主要方法:
- 对来自牛,绵羊和山羊的200个便,肠道和肝脏样本进行细菌学和生物化学分析.
- 聚合酶链反应 (PCR) 用于CP毒素基因类型.
- 对Moringa oleifera提取物 (油,乙醇,水) 和商业抗生素的抗菌敏感性测试和评估.
主要成果:
- 克洛斯特里透的患病率为51%,对四环素和林氏素有很高的耐药性.
- 莫林加油和乙醇提取物显示出显著的抗菌活性对抗CP分离物,抑制区高达24毫米.
- 莫林加油和乙醇提取物的疗效超过了一些经过测试的商业抗生素.
结论:
- 在农场动物中,Moringa oleifera表现出强大的抗菌特性,可以对农场动物的Clostridium perfringens产生抗菌作用.
- 这项研究表明,Moringa oleifera是抗生素的潜在天然替代品,可以解决抗生素耐药性的问题.
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