构建一个名图来预测UPJO的预后和复发风险
Wenyue Ma1, Hongjie Gao2, Mengmeng Chang1
1Department of Pediatric Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Frontiers in pediatrics
|April 18, 2024
概括
这项研究确定了尿道皮层结节阻塞 (UPJO) 复发和预后的关键风险因素. 使用这些因素的预测模型可以指导UPJO管理的临床决策.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术结果研究研究.
背景情况:
- 泌尿外皮交叉阻塞 (UPJO) 对预后和复发构成风险.
- 确定预测因素对于有效的临床管理至关重要.
研究的目的:
- 探索和识别与UPJO的预后和复发相关的风险因素.
- 开发UPJO结果的预测模型.
主要方法:
- 用二进制和多变量逻辑回归来分析相关性.
- 基于后勤回归结果构建了一个名图.
- 使用C统计,ROC曲线和决策曲线分析 (DCA) 评估模型性能.
主要成果:
- 手术前的自动腹膜透析 (APD),手术前的尿路感染 (UTI),手术前的关膜厚度 (RPT),梅奥粘合概率 (MAP) 评分和外科医生的熟练程度被确定为高风险因素.
- 纳入这五个变量的名图显示出有利的特异性,在自我交叉验证后AUC为0.8831.
结论:
- 基于五个关键因素开发的预测模型显示了UPJO预后和复发的良好预测能力.
- 该模型可以为UPJO的临床诊断和治疗策略提供有价值的指导.
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