马尼萨省西尼罗病毒血清流行:基于人口的研究
Abdurrahman Gülmez1, Ahmet Naci Emecen2, Mestan Emek3
1Medical Microbiology Laboratory, İstanbul Başakşehir Cam ve Sakura Hospital, İstanbul, Turkey.
Infectious diseases & clinical microbiology
|April 18, 2024
概括
土耳其马尼萨的西尼罗病毒 (WNV) 血清流行率为3.8%. 较高的WNV风险与年龄较大,收入较低和生活在较低的海拔地区有关.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 西尼罗河病毒 (WNV) 构成了全球和土耳其的重大公共卫生威胁.
- 基于社区的数据对于制定有效的WNV疫情预防策略至关重要.
- 这项研究解决了在马尼萨省对WNV监测的需求.
研究的目的:
- 为了确定西尼罗河病毒 (WNV) 在土耳其马尼萨的社区血清流行率.
- 调查WNV血清阳性与社会人口统计学和社会经济因素之间的关联.
- 为了确定研究群体中WNV感染的风险因素.
主要方法:
- 分析了来自马尼萨省家庭医学信息系统的1233名个人 (年龄大于2岁) 的简单随机样本.
- 血清样本使用商业ELISA测试以检测WNV特异性IgG抗体.
- 统计分析包括千平方,费舍尔的精确测试,t测试和逻辑回归来评估风险因素.
主要成果:
- 在3.8%的参与者中检测到WNV IgG抗体.
- 老年人,高血压患者,糖尿病患者,心血管疾病患者,受教育程度较低,收入较低的人群中,血清患病率明显较高.
- 多变量分析确定了高级年龄 (OR: 1.05),年收入 <3265 TL (OR: 3.21) 和生活在132米以下的海拔 (OR: 3.21) 作为重要的风险因素.
结论:
- 通过ELISA,曼尼萨省的WNV IgG血清流行率被确定为3.8%.
- 高龄,低收入和居住在低海拔地区与增加WNV血清阳性有显著的关联.
- 这些发现突出了影响该地区WNV风险的关键人口和环境因素.
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