艾滋病毒和SARS-Cov-2联合感染:一个当地观点
Heval Can Bilek1, Aydın Deveci1
1Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayıs University School of Medicine, Samsun, Turkey.
Infectious diseases & clinical microbiology
|April 18, 2024
概括
人类免疫缺陷病毒 (HIV) 和严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 联合感染并没有使COVID-19的结果恶化. 接受抗逆转录病毒疗法 (ART) 的艾滋病毒患者表现为轻度COVID-19,死亡率没有增加.
科学领域:
- 传染性疾病 传染性疾病
- 病毒学 病毒学
- 免疫学 免疫学 免疫学
背景情况:
- 由SARS-CoV-2引起的COVID-19大流行影响了全球健康.
- 在SARS-CoV-2阳性患者中与HIV的同时感染引起了对临床结果的担忧.
- 了解艾滋病毒和SARS-CoV-2之间的相互作用对于患者管理至关重要.
研究的目的:
- 评估HIV和SARS-CoV-2同时感染的患者的临床过程.
- 评估艾滋病毒对COVID-19严重性和死亡率的影响.
- 为管理同时感染的患者提供当地观点.
主要方法:
- 对HIV和SARS-CoV-2同时感染的患者的回顾性分析.
- 2020年3月至2021年6月,在土耳其的三级医院收集的数据.
- 包括30名同时感染的患者,分析人口统计,艾滋病毒状况,ART和COVID-19结果.
主要成果:
- 大多数同时感染的患者 (27/30) 经历了COVID-19的轻微进展.
- 三名患者被送往医院,其中两名是从未接受过ART的男性,不幸的是他们死亡.
- 所有已知的艾滋病毒阳性患者都接受了ART和病毒学抑制,没有增加COVID-19的严重程度.
结论:
- 仅仅艾滋病毒感染并没有增加COVID-19的严重程度.
- 艾滋病毒状况和ART坚持并没有显著增加COVID-19患者的死亡率.
- 被ART抑制的HIV患者表现出与一般人群相似的COVID-19临床过程.
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