在重症监护室吸入挥发性麻醉剂
Erin D Wieruszewski1, Mariam ElSaban2, Patrick M Wieruszewski1
1Department of Pharmacy, Mayo Clinic, Rochester, MN 55905, United States.
World journal of critical care medicine
|April 18, 2024
概括
挥发性麻醉剂现在用于集中治疗镇静和肺部疾病的重症监护. 它们的可定位性质提供了精确的患者管理,尽管培训和设备是障碍.
科学领域:
- 麻醉学 麻醉学
- 临界护理医学 临界护理医学
背景情况:
- 自19世纪以来,挥发性麻醉剂彻底改变了外科手术.
- 它们的使用正在扩大,超越手术室进入重症监护室 (ICU).
研究的目的:
- 探索在重症监护机构中挥发性麻醉剂的应用.
- 讨论它们的药理学,施用,并发症,适应症和危急病患者的证据.
主要方法:
- 对药理学和注射途径 (吸入,ECMO电路) 的审查.
- 对药物动力学概况进行定量和个性化管理的分析.
- 检查用于重症监护的指示和证据.
主要成果:
- 挥发性麻醉剂为复杂的镇静,耐火性肺部疾病 (ARDS,状态喘) 和神经疾病 (状态) 提供解决方案.
- 它们的可定位性质允许准确,个性化的患者管理,可能降低传统镇静剂的风险.
结论:
- 挥发性麻醉剂在重症监护中是一个有前途的治疗选择.
- 更广泛的采用障碍包括设备的可用性,员工培训和熟悉安全使用协议.
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