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Hüseyin Bilgin¹, Tuğçe Başarı¹, Nazlı Pazar¹

¹Department of Infectious Diseases and Clinical Microbiology, Marmara University School of Medicine, İstanbul, Türkiye.

Infectious diseases & clinical microbiology

|April 18, 2024

概括

与社区获得的流感 (CAI) 相比,医院获得的流感 (HAI) 显著增加了28天死亡的风险. 强有力的感染控制对于降低医院获得的病毒感染死亡率至关重要.

科学领域:

传染性疾病传染性疾病
流行病学流行病学
医院流行病学医院流行病学

背景情况:

流感仍然是致病率和死亡率的重要原因.
区分医院获得的流感 (HAI) 和社区获得的流感 (CAI) 对于了解患者的结果至关重要.
医院感染对患者安全和医疗保健系统构成重大威胁.

研究的目的:

为了比较HAI和CAI患者之间的28天死亡率.
确定与住院流感患者死亡率相关的风险因素.
强调医疗保健机构内病毒感染感染控制的重要性.

主要方法:

对17岁以上确诊流感的住院患者进行了回顾性队列研究.
HAI定义为在入院后72小时内诊断出流感;CAI在入院前72小时内诊断出流感.
对年龄,性别,并发症和ICU入院进行调整的后勤回归分析,以确定死亡率预测因素.

主要成果:

在201名患者中,92人 (46%) 患有HAI,109人患有CAI.
多变量分析显示,HAI与28天死亡率增加5.6倍相关 (95%CI=1.6-19.3;p=0.006).
在对非幸存者的单变量分析中,ICU入院被确定为一个重要的因素.

结论:

与CAI患者相比,HAI患者面临的28天死亡风险明显高于CAI患者,即使经过对混因素的调整.
HAI的高发病率凸显了严格的感染控制措施的迫切需要.
进一步的研究和有针对性的干预措施对于减轻HAI的影响和改善结果至关重要.

关键词:

接种流感疫苗可以预防流感交叉感染交叉感染在医院获得的病毒性疾病.人类人类人类人类人类人类人类流感流感流感流感流感死亡率死亡率

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