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活检前MRI和额外测试对前列腺癌查结果的影响:快速审查

Abel Tesfai¹, Natalia Norori¹, Thomas A Harding¹

¹Prostate Cancer UK London UK.

|April 18, 2024

概括

活检前的MRI与PSA检测相结合,可以改善显著前列腺癌的检测,并减少不必要的活检. 需要对死亡率等长期结果进行进一步的研究.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
在瘤学瘤学.
放射学放射学是一门学科.

背景情况:

前列腺癌的诊断依赖于前列腺特异性抗原 (PSA) 测试和活检.
活检前磁共振成像 (MRI) 越来越多地用于指导前列腺癌检测.
整合MRI与PSA测试对患者结局的影响需要全面评估.

研究的目的:

审查最新证据,以检查MRI和PSA检测的影响.
评估前列腺癌诊断对健康结果和生活质量的影响.
为了比较MRI引导的方法与标准的活检方法.

主要方法:

在PubMed和Cochrane CENTRAL (2005-2023) 的系统文献搜索.
包括随机对照试验 (RCT) 和队列研究.
对比PSA检测,MRI (mpMRI,bpMRI) 和活检策略的研究分析.

主要成果:

基于MRI的策略增加了临床显著前列腺癌的检测.
核磁共振扫描减少了临床上无意义癌症的诊断 (格里森3+3).
磁力共振扫描使8%-49%的男性能够避免活检,尽管不是普遍的.
观察到低血症和尿路感染 (UTI) 的发生率.

结论:

活检前MRI与PSA测试相结合,可以提高临床上显著的癌症检测.
这种方法可以减少微不足道的癌症的诊断和不必要的活检.
长期影响,包括前列腺癌特异性死亡率,仍未评估.

关键词:

这就是为什么PSAPSAPSA.这是bpMRI.mpMRI 的时间.过度诊断是一种过度诊断生物检查前的预先检查

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