眼科检查和心声检查应该是白血病治疗的重要组成部分
Çiğdem Erol1, Nuran Sarı1, Tuğba Yanık-Yalçın1
1Department of Infectious Diseases and Clinical Microbiology, Başkent University School of Medicine, Ankara, Turkey.
Infectious diseases & clinical microbiology
|April 18, 2024
概括
кандидеми的发病率显著增加,死亡率高,特别是在某些Candida物种. 早期诊断和全面的抗真菌管理对于更好的患者结果至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 医学真菌学 医学真菌学
- 关键护理医学 关键护理医学
背景情况:
- 疹病是一种由Candida物种引起的血液感染,是致病率和死亡率的重要原因.
- 它与严重的并发症有关,如末端器官参与,长时间住院和增加医疗保健费用.
- 我们中心之前的数据突出显示了候选血病的负担,需要更新的流行病学见解.
研究的目的:
- 为了确定当前候选血病发作的发生率和特征.
- 将当代数据与我们机构的历史发现进行比较.
- 确定风险因素和结果,包括死亡率和转移性感染.
主要方法:
- 一个单一中心的回顾性观察研究包括250名在2015年1月至2020年12月期间被诊断患有白血病的成年患者.
- 从医疗记录中收集了人口统计,临床,实验室和治疗数据.
- 在诊断后的第一周内进行了眼科检查和心声扫描,以选转移性感染.
主要成果:
- 确诊了275次白血病发作,与以前的报告相比,发病率增加 (2.8/1000例).
- 最常见的物种是Candida albicans (41.8%),其次是Candida glabrata (22.2%),在重症患者中更为普遍.
- 30天死亡率为44.7%,C. glabrata和Candida krusei感染的死亡率更高. 住院治疗,并发症和先前使用抗生素与死亡率有关.
结论:
- 候选血病的发病率有所上升,这强调了需要加强监测和管理策略的需要.
- 高死亡率和严重并发症的可能性,如内心炎,需要及时诊断和治疗.
- 实施全面的候群病包和抗真菌管理计划对于改善患者的治疗结果和降低医疗保健成本至关重要.
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