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Updated: Jun 28, 2025

Spatial and Temporal Control of T Cell Activation Using a Photoactivatable Agonist
07:48

Spatial and Temporal Control of T Cell Activation Using a Photoactivatable Agonist

Published on: April 25, 2018

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空间时间控制的T细胞组合疗法用于固体瘤

Meixi Hao1,2, Ying Zhou1,2, Sijia Chen1,2

  • 1State Key Laboratory of Natural Medicines, Center of Advanced Pharmaceuticals and Biomaterials, China Pharmaceutical University, Nanjing, 211198, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|April 18, 2024
PubMed
概括

这项研究开发了一种新型的三重疗法,将T细胞与印度莱胺2,3-二氧化原酶抑制剂和循环素依赖性激酶4/6抑制剂结合起来. 这种基于细胞的创新疗法有效地抑制了固体瘤,并改善了小鼠的生存率.

关键词:
治疗T细胞疗法核心外结构化的纳米粒子.特定地点的药物释放.空间时间控制的细胞制药.三重药物组合是三重的药物组合.

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