在中国上海COVID-19大流行后,呼吸道病原体感染模式的变化在中国上海发生
Muyun Wei1, Shuangshuang Li1, Xinhua Lu1
1Department of Laboratory Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Journal of medical virology
|April 18, 2024
概括
2023年呼吸道病原体的发病率显示,儿童受到影响最大. 现在Mycoplasma pneumoniae在儿童中占主导地位,取代了人类呼吸道同胞病毒 (HRSV).
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 微生物学 微生物学
背景情况:
- 后COVID-19流行性呼吸道感染模式需要更新分析.
- 了解病原体患病率对于公共卫生战略至关重要.
研究的目的:
- 在2023年评估11种常见的呼吸道病原体的阳性率.
- 分析不同年龄组和免疫状况的呼吸道感染模式.
主要方法:
- 多重聚合酶连锁反应 (PCR) 测试在7544个住院患者样本上.
- 分析2022年7月至2023年12月的病原体数据.
- 根据年龄,免疫状况和慢性呼吸道疾病对结果的分层.
主要成果:
- 至少一种病原体的整体阳性率为26.07%.
- 儿童 (55.18%) 的感染率明显高于成人 (20.88%) 和老年人 (20.66%).
- 流感A型病毒 (8.63%),肺炎菌 (5.47%) 和人类鼻膜病毒 (5.12%) 是最常见的;M. pneumoniae取代了HRSV作为儿童的主导病原体.
结论:
- 呼吸道感染模式在流行病后和控制措施后发生了变化.
- 儿童和免疫受损的个体患呼吸道感染和混合感染的风险更高.
- 像M. pneumoniae这样的特定病原体的患病率呈现变化,特别是在儿童群体中.
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