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Updated: Jun 28, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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基调节剂的药理学表征:对于化学因子受体的一个例子

Lisa S den Hollander1, Adriaan P IJzerman1, Laura H Heitman1,2

  • 1Leiden Academic Centre for Drug Research, Division of Drug Discovery and Safety, Leiden, The Netherlands.

Medicinal research reviews
|April 18, 2024
PubMed
概括

基调制剂为开发向化学因受体的新药提供了一个有前途的途径,克服了免疫疾病治疗中的高消耗率. 这些化合物提供受控的受体调节,增强的选择性,并改善药物的疗效.

关键词:
通过全osteric 调制.化学因子受体的化学因子受体医学化学 医学化学分子药理学分子药理学

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