与原发性和治疗后的顶部牙周炎相关的顶部根管微生物组:系统性审查
José F Siqueira1,2, Warley O Silva1, Kaline Romeiro1
1Postgraduate Program in Dentistry, University of Grande Rio (UNIGRANRIO), Rio de Janeiro, RJ, Brazil.
International endodontic journal
|April 18, 2024
概括
顶部根管微生物组在初级和治疗后的顶部牙周炎中显示出显著的细菌多样性. 根据感染类型观察到不同的微生物组成,具有很高的个体间变异性.
科学领域:
- 微生物学 微生物学
- 牙周内科医院 牙周内科医院 牙周内科医院
- 口腔健康 口腔健康
背景情况:
- 顶端根管系统中的微生物是导致和维持顶端牙周炎的关键.
- 牙周周膜炎是牙周周膜组织的炎症状况.
研究的目的:
- 系统地审查研究的微生物组,仅限于牙的顶端根通道的牙的初级和治疗后的顶端牙周炎.
主要方法:
- 在2023年8月之前搜索了PubMed,Embase,科学网,科学直播和Proquest.
- 包括使用培养和分子方法识别角根管段中的微生物种群的临床研究.
- 使用乔安娜·布里格斯研究所的临界患病率评估检查清单评估研究.
主要成果:
- 包括21项研究,19项使用分子方法,2项使用培养方法.
- 在初级感染中最常见的细菌包括Pseudoramibacter alactolyticus,Olsenella uli和Fusobacterium spp.
- 在治疗后感染中常见的细菌包括Streptococcus spp.,Enterococcus spp.和Fusobacterium spp.
- 细菌类是代表性最大的细菌类,细菌负载在初级感染中从10^5到10^6不等,在治疗后感染中从10^3到10^4.
结论:
- 在受感染的尾通道中存在明显的细菌多样性,具有很高的个体间变异性.
- 在初级和治疗后的顶部牙周炎之间,微生物组的组成有显著差异.
- 方法的异质性限制了最终的结论,并阻止了元分析.
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