Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Bioremediation00:46

Bioremediation

18.3K
Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
18.3K
Fates of Pyruvate01:20

Fates of Pyruvate

8.4K
Pyruvate is the end product of glycolysis, where glucose is oxidized to pyruvate, simultaneously reducing NAD+ to NADH. Two molecules of ATP are also produced by substrate-level phosphorylation.
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
8.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Before LUCA: unearthing the chemical roots of metabolism.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2025
Same author

Challenges and Opportunities in Smart Biosensing for Biomanufacturing.

ACS synthetic biology·2025
Same author

Context-Aware Biosensor Design Through Biology-Guided Machine Learning and Dynamical Modeling.

ACS synthetic biology·2025
Same author

The automated Galaxy-SynBioCAD pipeline for synthetic biology design and engineering.

Nature communications·2022
Same author

Prototyping of microbial chassis for the biomanufacturing of high-value chemical targets.

Biochemical Society transactions·2021
Same author

<i>In silico</i> design and automated learning to boost next-generation smart biomanufacturing.

Synthetic biology (Oxford, England)·2020
Same journal

Correction to 'scSuperAnnotator: A platform for benchmarking comparison and visualizing automated cellular annotation methods for scRNA-seq data'.

Nucleic acids research·2026
Same journal

Correction to 'Differentiable partition function calculation for RNA'.

Nucleic acids research·2026
Same journal

Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and changing m6A modification in U1 and U6 snRNA.

Nucleic acids research·2026
Same journal

Bacillus subtilis DnaB forms multiple protein-protein interactions essential for DNA replication initiation.

Nucleic acids research·2026
Same journal

Multiple forms of protein-protein and DNA binding are exhibited by BrxC from the BREX phage restriction system.

Nucleic acids research·2026
Same journal

Biosynthesis of glycosylated 5-hydroxycytosine in the DNA of diverse viruses.

Nucleic acids research·2026
查看所有相关文章

相关实验视频

Updated: Jun 28, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
07:59

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

9.8K

DetSpace:一个用于设计可检测的生物化学生产路径的Web服务器.

Hèctor Martín Lázaro1, Ricardo Marín Bautista1, Pablo Carbonell1,2

  • 1Institute of Industrial Control Systems and Computing (AI2), Universitat Politècnica de València (UPV), Camí de Vera s/n, 46022 València, Spain.

Nucleic acids research
|April 18, 2024
PubMed
概括
此摘要是机器生成的。

开发可持续的生物基化学品需要高效的生产. DetSpace网络服务器提供了一个系统的方法来设计遗传电路,使精确的生物传感和代谢途径的动态调节,以改善生物经济应用.

更多相关视频

GENPLAT: an Automated Platform for Biomass Enzyme Discovery and Cocktail Optimization
11:38

GENPLAT: an Automated Platform for Biomass Enzyme Discovery and Cocktail Optimization

Published on: October 24, 2011

15.5K
Light-Controlled Fermentations for Microbial Chemical and Protein Production
08:37

Light-Controlled Fermentations for Microbial Chemical and Protein Production

Published on: March 22, 2022

4.0K

相关实验视频

Last Updated: Jun 28, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
07:59

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

9.8K
GENPLAT: an Automated Platform for Biomass Enzyme Discovery and Cocktail Optimization
11:38

GENPLAT: an Automated Platform for Biomass Enzyme Discovery and Cocktail Optimization

Published on: October 24, 2011

15.5K
Light-Controlled Fermentations for Microbial Chemical and Protein Production
08:37

Light-Controlled Fermentations for Microbial Chemical and Protein Production

Published on: March 22, 2022

4.0K

科学领域:

  • 合成生物学 合成生物学
  • 代谢工程是代谢工程.
  • 生物经济是生物经济.

背景情况:

  • 气候变化需要通过生物多样性实现可持续的化学生产.
  • 目前的生物化工生产面临着可扩展性和效率的挑战 (定量,速度,产量).
  • 自动选和生物传感器有助于优化菌株,但缺乏系统的遗传电路设计来感知标化合物.

研究的目的:

  • 介绍DetSpace,一个用于设计对特定分子响应的遗传电路的Web服务器.
  • 为了使合成生物学家能够为动态代谢途径调节创造生物传感路径.

主要方法:

  • 使用集成工具开发DetSpace网络服务器.
  • 通过酶转化为可检测信号来设计分子传感的生物电路的便利化.
  • 用于信号传导的转录因子的整合.

主要成果:

  • DetSpace提供了一个系统的方法来设计分子响应的遗传电路.
  • 能够创建生物传感路径,用于动态路径调节.
  • 支持基因电路设计,选,生产,生物修复,诊断和药物输送中的应用.

结论:

  • DetSpace使合成生物学家能够克服生物化学生产中的障碍.
  • 促进生物经济的生物化学品的高效和可扩展的生产.
  • 扩大生物传感在各种生物技术领域的应用.