细胞巨乳病毒感染是大肠炎的罕见原因
José María Rodríguez Lucas1, Emilio Peña Ros2, Francisco Miguel González Valverde3
1Cirugía General y del Aparato Digestivo, Hospital General Universitario Reina Sofía, España.
Revista espanola de enfermedades digestivas
|April 18, 2024
概括
细胞巨乳病毒 (CMV) 感染可能导致化疗后患者的结肠炎. 在这种情况下,迅速的甘西克洛维尔治疗导致了临床改善和愈.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 在瘤学瘤学.
背景情况:
- 细胞巨乳病毒 (CMV) 感染是免疫功能低下的患者,特别是那些因直肠癌接受化疗的患者的一个重大问题.
- 结直肠手术和结直肠关闭后的术后并发症可能会带来诊断挑战.
研究的目的:
- 报告发生在直肠外科手术和化疗后出现的细胞巨乳病毒 (CMV) 大肠炎病例.
- 要突出诊断方法和成功治疗的CMV感染在免疫功能低下的患者.
主要方法:
- 一名62岁的男性患者接受了低前直肠切除,接受了新辅助化疗和放射治疗,随后进行了大肠切除关闭.
- 诊断工作包括腹部CT扫描,结肠镜与活检,便培养和CMV血清学.
- 治疗涉及基于疑似CMV感染的甘西克洛维尔的管理.
主要成果:
- 患者在术后出现发烧和腹,CT扫描显示大肠炎,结肠镜检查显示特征深直肠.
- 虽然活检和便培养结果呈阴性,但CMV血清学证实了感染.
- 用甘西克洛维尔治疗导致临床改善,症状的消失,以及愈的内镜证据.
结论:
- 在化学疗法和手术后出现胃肠道症状的免疫受损患者中,应考虑细胞巨乳病毒 (CMV) 大肠炎.
- 早期诊断和甘西克洛维尔治疗对于CMV感染的良好结果至关重要.
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