降低抗生素剂量对为复杂尾炎进行尾切除术的儿科患者的影响
Monique Motta1, Nikitha Garapaty2, Margaret Savage2
1Department of Surgery, Memorial Healthcare System, Hollywood, FL, USA.
The American surgeon
|April 18, 2024
概括
对于患有尾炎并发症的小儿尾切除术患者,额外的手术前抗生素剂量并没有显著降低手术部位感染 (SSI) 率. 目前的协议可能不需要在切口时间更接近的抗生素再剂量.
科学领域:
- 儿科手术 儿科手术
- 传染性疾病 传染性疾病
- 抗生素管理局 抗生素管理局
背景情况:
- 缺乏标准化的手术前抗生素协议,用于复杂尾炎的儿科尾切除术.
- 缓解手术部位感染 (SSIs) 需要平衡有效的抗生素使用与尽量减少暴露.
研究的目的:
- 为了比较小儿科患者进行腹腔镜尾切除术并发尾炎的SSI,接受单次手术前抗生素剂量与接受额外剂量的SSI.
主要方法:
- 在2020年至2022年期间,对124名儿科患者进行了回顾性图表审查.
- 在接受一剂与多剂手术前抗生素剂量的患者之间,SSI率的比较.
主要成果:
- 18%的患者接受了额外的手术前抗生素剂量.
- 两组之间没有观察到SSI率的统计学上显著差异 (P值 = .352).
结论:
- 更接近切口时间的抗生素减少剂量可能不会影响该患者群体的SSI率.
- 需要进行进一步的研究,以确定术前抗生素给药的最终临床建议.
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