整感受性大脑网络的与年龄相关的变化:对整感受和alexithymia的影响
Olga R Dobrushina1, Larisa A Dobrynina1, Galina A Arina2
1Department of Neurology, Research Center of Neurology.
Emotion (Washington, D.C.)
|April 18, 2024
概括
衰老会损害整体感受,并通过影响大脑活动和连接性来增加alexithymia. 这种降低了对身体的感觉.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 老年学是一门学科.
背景情况:
- 衰老与减少感知能力和改变情绪处理有关,例如alexithymia.
- 参与整体感受的大脑区域也在情绪感知中发挥作用,这表明潜在的共享神经基础.
研究的目的:
- 为了研究衰老,感官衰退和alexithymia之间的关系背后的神经机制.
- 探索大脑激活和连接的与年龄相关的变化如何调解这些过程.
主要方法:
- 功能磁共振成像 (fMRI) 在心跳检测任务期间.
- 使用问卷评估整感觉敏感性,亚历克西西米亚和抑郁态度.
- 路径分析以检查神经变量对与年龄相关的结果的中介效应.
主要成果:
- 年龄较大与在整体受理期间岛内皮层和补充运动区域 (SMAs) 的激活减少相关.
- 观察到与年龄相关的功能连接性变化,包括SMA岛屿连接性降低和前额外侧部网络连接性增加.
- 互感性衰退调解了年龄对alexithymia的影响,神经激活和连接性发挥了调解作用.
结论:
- 中枢神经机制是与年龄相关的感觉衰退及其与alexithymia的关联的基础.
- 研究结果强调了整感变化对老年人的精神健康的影响.
- 了解这些机制可能会为支持健康衰老和减轻与alexithymia相关的风险的策略提供信息.
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