在拉丁美洲,由于急性呼吸窘迫综合征的死亡率
Roberto Santa Cruz1,2,3, Amelia Matesa4, Antonella Gómez5,6
1Hospital General Ramos Mejía, Ciudad Autónoma de Buenos Aires, Argentina.
Critical care medicine
|April 18, 2024
概括
拉丁美洲的急性呼吸困难综合征 (ARDS) 死亡率高达52%. 本次审查强调了急需改善该地区ARDS管理战略的迫切需要.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 流行病学 流行病学
背景情况:
- 急性呼吸困难综合征 (ARDS) 是一个重大的全球健康挑战.
- 关于ARDS的流行病学数据对于有效管理和资源分配至关重要.
- 现有的ARDS死亡率数据主要来自高收入国家.
研究的目的:
- 评估急性呼吸困难综合征 (ARDS) 死亡率,特别是在拉丁美洲.
- 综合拉丁美洲地区ARDS流行病学现有证据.
- 为拉丁美洲的ARDS护理制定有针对性的干预措施和资源优化提供信息.
主要方法:
- 从1967年到2023年3月,在主要数据库 (PubMed,Cochrane,Web of Science,LILACS) 进行了全面的文献搜索.
- 使用随机效应模型,对比例进行了元分析,从符合条件的观察性研究和随机对照试验中汇集死亡率数据.
- 进行了敏感性,子组和元回归分析,以探索基于研究设计,诊断标准 (柏林定义,PaO2 / FiO2比率),出版期和地理位置的死亡率变化.
主要成果:
- 总共有32项涉及3627名患者的研究被纳入了分析.
- 拉丁美洲ARDS的综合死亡率为52% (证据确定性低).
- 使用柏林定义的灵敏度分析表明死亡率为46% (证据的适度确定性),在子组和区域中观察到差异.
结论:
- 拉丁美洲与ARDS相关的死亡率仍然很高,与全球其他地区相比.
- 这些发现强调了战略规划和实施措施的必要性,以改善拉丁美洲ARDS患者的治疗结果.
- 这些证据作为开发和加强该地区ARDS管理和治疗方案的基础.
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