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Updated: Jun 28, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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Published on: April 4, 2018

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在全球人口中,癌症相关的人类激酶中具有有害变异的诱导性

Salman Ahmed Khan1,2, Misbah Anwar3, Atia Gohar4

  • 1Department of Molecular Medicine (DMM), Dow College of Biotechnology (DCoB), Dow University of Health Sciences (DUHS), Karachi, Pakistan.

PloS one
|April 18, 2024
PubMed
概括

这项研究分析了超过6.5万个人的酶基因突变,确定了与癌症有关的有害突变. 它强调了NTRK1和FGFR3作为关键基因,并提出了针对个性化癌症治疗的潜在药物.

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