人类关闭的功能连接性,根据人类连接组项目数据库
Lluviana Rodríguez-Vidal1, Sarael Alcauter1, Fernando A Barrios1
1Universidad Nacional Autónoma de México, Instituto de Neurobiología, Querétaro, Querétaro, México.
PloS one
|April 18, 2024
概括
关闭体,一个大脑结构,连接到关键网络,如前端对象网络,影响认知任务. 这项研究揭示了其独特的功能连接模式,并突出了潜在的大脑不对称性.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 神经成像是一种神经成像.
背景情况:
- 关闭体,是脑袋中的灰色物质片,涉及突出处理和感官集成.
- 之前的研究表明与岛屿皮层的协作激活,并报告不对称性,特别是在神经系统疾病,如阿尔茨海默氏症和精神分裂症.
研究的目的:
- 通过静止状态fMRI数据,研究关闭体的功能连接性.
- 为了测试这个假设,闭膜是多个大脑网络中的一个节点,在连接方面与岛屿皮层不同,并表现出不对称性.
主要方法:
- 分析了休息状态的功能和解剖学MRI数据,这些数据来自100名来自人类结合体项目 (HCP) 的健康受试者.
- 沃克塞尔分辨率为2x2x2 mm3.3 的2x2x2 mm3.
主要成果:
- 关闭层与至少三个不同的大脑网络相连.
- 发现了关闭体,前面对面网络和默认模式网络之间的显著功能连接.
- 观察到右侧关节与前侧双侧和背侧注意力网络的连接性,支持关节不对称.
结论:
- 闭关体作为多个大脑网络中的一个节点,特别是前侧双相网络.
- 闭层的功能连接模式与岛屿皮层不同.
- 有证据表明,关闭的功能连接存在不对称性,可能会影响认知过程.
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