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相关概念视频

Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

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Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
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Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

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The pathophysiology of pneumonia involves the following steps:
262
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

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Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
230
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

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Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
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Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Pneumonia IV: Management01:28

Pneumonia IV: Management

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The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
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相关实验视频

Updated: Jun 28, 2025

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
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在COVID-19患者中发生的细菌和真菌二次感染,在重症监护中随访:一项回顾性研究.

Erhan Ozyurt1, Aylin Erman Daloglu2, Kerem Inanoglu1

  • 1Department of Anesthesiology and Reanimation, Antalya Training and Research Hospital, University of Health Sciences, Antalya, Turkey.

Journal of infection in developing countries
|April 18, 2024
PubMed
概括
此摘要是机器生成的。

二次细菌和真菌感染显著增加了COVID-19患者的死亡率和重症监护室 (ICU) 停留时间. 格拉姆阴性病原体,特别是在呼吸道感染中,是最常见的,导致更糟糕的结果.

关键词:
在 COVID-19 疫情中,重症监护室的重症监护室是重症监护室的重症监护室.二次性感染的第二次感染.

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科学领域:

  • 传染性疾病 传染性疾病
  • 临界护理医学 临界护理医学
  • 病毒学 病毒学

背景情况:

  • 进入重症监护室 (ICU) 的2019年新冠病毒病 (COVID-19) 患者容易发生二次细菌和真菌感染.
  • 了解这些二次感染对患者结果的影响对于改善护理至关重要.

研究的目的:

  • 调查二次细菌和真菌感染对在ICU管理的COVID-19患者的患者结果的影响.
  • 确定常见的病原体及其对逗留时间和死亡率的影响.

主要方法:

  • 在2020年3月至2021年6月期间,251名逆转录酶聚合酶连锁反应 (RT-PCR) 阳性COVID-19患者被录入ICU的回顾性分析.
  • 收集的数据包括人口统计数据,二次感染病原体,发病时间和患者结局.
  • 研究人员检查了血液,尿液,呼吸道和导管的培养物.

主要成果:

  • 超过一半的患者 (51.4%) 患有至少一种二次感染,呼吸道感染是最常见的 (41.4%).
  • 主要的病原体是グラム阴性细菌 (58.4%),以及Candida spp. 在尿液培养中常见.
  • 患有二次感染的患者在ICU停留时间 (LOS) 显著长,死亡率更高 (p < 0.001).

结论:

  • 二次性感染,特别是呼吸道中的格拉姆阴性细菌感染,是ICU管理的COVID-19患者的重大并发症.
  • 这些感染与长时间的ICU住院和增加的死亡率有关.
  • 对二次感染的有效管理策略对于改善COVID-19患者的治疗结果至关重要.