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远程嗅觉评估使用NIH工具箱气味识别测试和大脑健康登记册
Cristina Jaén1, Christopher Maute1, Scott Mackin2,3
1Monell Chemical Senses Center, Philadelphia, Pennsylvania, United States of America.
PloS one
|April 18, 2024
概括
早期发现嗅觉缺陷至关重要. 美国国立卫生研究院工具箱气味识别测试可实现远程自我管理,在流行病学研究中证明对人口层面的嗅觉评估有效.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 流行病学 流行病学
背景情况:
- 嗅觉功能障碍与衰老和神经退行性疾病有关.
- 早期识别嗅觉缺陷对于及时干预至关重要.
- 人口层面的嗅觉评估需要可访问的,远程测试方法.
研究的目的:
- 评估使用NIH工具箱气味识别测试进行远程嗅觉测试的可行性.
- 评估非专有嗅觉测试对大规模研究的有用性.
- 为了确定测试是否可以捕捉与年龄和性别相关的嗅觉性能差异.
主要方法:
- 从在线大脑健康登记处招募了39岁以上的参与者.
- 美国国立卫生研究院工具箱气味识别测试 (NIH Toolbox Odor ID Test) 被邮寄给参与者,以便在家自行使用.
- 家庭管理的测试数据与规范数据进行了比较,并与气味识别测试进行了验证.
主要成果:
- 自行管理准确地反映了与年龄相关的嗅觉衰退.
- 女人表现出比男性更高的准确性,控制年龄.
- 该测试显示了与人体管理相比的性能.
结论:
- 美国国立卫生研究院工具箱气味识别测试适用于自行进行嗅觉评估.
- 远程测试增加了嗅觉测试在流行病学研究中的实用性.
- 这种可访问的方法是有价值的,当在人体检测是不可行的.
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