腰与身高的比例与老年人认知功能之间的关联
Huajuan Tang1, Qian Li1, Chuan Du2
1Department of Neurology, 363 Hospital, Chengdu, People's Republic of China.
Nutritional neuroscience
|April 18, 2024
概括
以腰与身高比率 (WHtR) 衡量的中心肥胖与老年人认知功能较差有关. 较高的WHtR表明认知能力下降的风险增加,强调保持健康体重对大脑健康的重要性.
科学领域:
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
- 心血管健康 心血管健康
背景情况:
- 中部肥胖,以腰与身高的比率 (WHtR) 表示,是关键的健康指标.
- 关于WHtR与美国老年人的认知功能之间存在联系的研究有限.
研究的目的:
- 研究WHtR与老年人认知功能之间的关联.
- 探索潜在的非线性关系和子组差异.
主要方法:
- 利用了2011-2014年国家健康和营养检查调查 (NHANES) 中65岁以上的1709名参与者的数据.
- 从测量的腰围和身高计算出WHtR.
- 通过数字符号替换测试评估认知功能,并分析了与加权多重线性回归和平滑曲线拟合的关联.
主要成果:
- 发现WHtR与认知功能 (β = -36.91,P < 0.001) 之间存在显著的负相关性,即使经过对混因素进行调整.
- 这种负相关性在性别和种族群体中持续存在.
- 在女性中观察到一个反转的U形曲线,在WHtR = 0.68.6的拐点.
结论:
- 较高的WHtR与老年人的认知功能下降有关.
- 中部肥胖可能会对晚年生活中的认知健康产生负面影响.
- 研究结果强调WHtR是老年人群认知风险的潜在生物标志物.
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