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适应性重置的微流体贴片用于汗流率和电解质检测.

Mengyuan Liu1, Siyuan Liu1, Tong Zhang1

  • 1School of Nano-Tech and Nano-Bionics, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui, 230026, PR China; i-Lab, Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO), Chinese Academy of Sciences (CAS), 398 Ruoshui Road, Suzhou, Jiangsu, 215123, PR China.

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概括

这项研究引入了一种可重置的微流体汗水贴片,用于持续的汗水监测. 该设备克服了重复使用和容量的限制,使得实际评估水分状态成为可能.

关键词:
微流体补丁 微流体补丁可重新设置的通道频道.流汗的损失 流汗的损失汗流率 汗流率 汗流率 汗流率汗水传感器可以检测出汗.

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科学领域:

  • 生物医学工程 生物医学工程
  • 微流体学 微流体学
  • 可穿戴技术可穿戴技术

背景情况:

  • 皮肤接口微流体贴片用于汗水分析.
  • 目前的局限性包括微通道重复使用的困难和限制的体积容量,阻碍了实际应用.

研究的目的:

  • 开发一种可自适应重置的微流体汗水贴片 (Art-Sweat贴片) 用于持续的汗流率和离子电荷度监测.
  • 为了提高微流体汗液传感器的稳定性和体积容量,用于实际的水分评估.

主要方法:

  • 开发了一个平台,结合了垂直和水平的微通道,用于反复填充和排空汗.
  • 集成的自适应体积变化识别用于传感器重置.
  • 嵌入自行设计的无线传输模块用于数据监控.

主要成果:

  • 证明持续监测出汗率 (0.2-4.0μL min-1) 和离子电荷度 (10-200 mmol L-1).
  • 实现了超过300μL的扩大体积容量,增强了稳定性.
  • 展示了产品层面的可穿戴性和在监测区域汗水变异方面的高性能.

结论:

  • 艺术汗水补丁为当前汗水传感器的可重复使用性和容量限制提供了解决方案.
  • 该设备可以准确和持续地监测汗液生物标志物,以有效评估水分状态.
  • 这项技术有望在可穿戴健康监测中的实际应用.