系统性免疫炎症指数与急性缺血性中风后的心脏并发症有关:一项回顾性单中心研究
Xiaodi Hao1, Mingfang Zhu1, Zhengyu Sun1
1Department of Neurology, Zhengzhou University People's Hospital, Zhengzhou University, Zhengzhou, Henan 450003, China.
Clinical neurology and neurosurgery
|April 18, 2024
概括
早期系统性免疫炎症 (SII) 指数在患有中风诱导心脏综合征的患者中较高. 这个指数独立地预测了急性缺血性中风后的心脏并发症.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 免疫学 免疫学 免疫学
背景情况:
- 脑卒中引起的心脏综合征是缺血性中风的常见和严重并发症.
- 它与患者预后不佳有关,需要对其机制进行进一步研究.
- 了解这些机制对于改善临床决策至关重要.
研究的目的:
- 研究急性缺血性中风后早期系统性免疫炎症 (SII) 指数和心脏并发症之间的关联.
- 确定SII指数是否可以预测中风心脏综合征的发展.
主要方法:
- 从2020年1月到2022年8月,对急性缺血性中风患者进行前性收集和回顾性分析.
- 纳入标准:症状出现后24小时内出现,没有感染或癌症.
- 从入院实验室数据计算SII指数 (中性粒细胞 × 血小板/淋巴细胞) / 1000.
主要成果:
- 分析了121名患者;24人 (19.8%) 在14天内出现心脏并发症.
- 患有中风心脏综合征的患者表现出明显更高的SII水平 (p<.001).
- SII指数是中风心脏综合征的独立预测指标 (aOR 5.089,p=.002).
结论:
- 在中风后出现的新发性心血管并发症很常见.
- 早期的全身免疫炎症 (SII) 指数与这些并发症密切相关.
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