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相关概念视频

Bioavailability Enhancement: Drug Stability Enhancement and GI Retention01:05

Bioavailability Enhancement: Drug Stability Enhancement and GI Retention

Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
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Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...

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相关实验视频

Updated: Jun 29, 2026

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
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尿路支架的最新发展:基板材料,涂层聚合物和技术,治疗功能.

Kai-Chao Wen1, Zheng-An Li1, Ji-Heng Liu2

  • 1School of Medicine, Shanghai University, Shanghai 200444, China; Department of Urology/Pharmaceutics, Shanghai Eighth People's Hospital, Shanghai 200235, China.

Colloids and surfaces. B, Biointerfaces
|April 18, 2024
PubMed
概括

尿管支架上的功能性涂层有效地防止细菌殖民和泌尿外科手术后的并发症. 本次审查强调了支架材料和涂料的进步,以提高治疗疗效.

关键词:
涂层材料的涂层材料是什么涂层制备 涂层制备功能应用程序 功能应用程序尿道支架 尿道支架

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科学领域:

  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科
  • 生物材料科学 生物材料科学
  • 药物运输 药物运输 药物运输

背景情况:

  • 尿道支架在泌尿外科手术后的临床尿道狭窄治疗中至关重要.
  • 细菌殖民和相关并发症仍然是当前尿路支架的重大挑战.

研究的目的:

  • 审查尿道支架的材料和功能性涂层.
  • 分析尿道支架功能涂料的技术进步.
  • 探索最近在提高功能性涂料治疗疗效方面取得的进展.

主要方法:

  • 关于尿道支架材料和涂层的综合文献综述.
  • 对材料特性和活性物质属性的分析.
  • 评估技术进步和提高治疗疗效.

主要成果:

  • 功能性涂料在抑制细菌殖民和减少并发症方面表现有前途.
  • 在先进的尿道支架涂层中使用了各种材料和活性物质.
  • 技术创新正在提高尿路支架的性能和治疗结果.

结论:

  • 功能性涂层是改善尿路支架性能和患者结果的关键.
  • 需要对含有药物的尿路支架进行进一步的研究.
  • 本综述为开发下一代尿路支架提供了洞察力.