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Updated: Jun 28, 2025

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整合多重成像和多尺度建模,确定瘤表型转化是治疗T细胞疗效的关键组成部分

John W Hickey1, Eran Agmon2, Nina Horowitz3

  • 1Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.

Cell systems
|April 18, 2024
PubMed
概括

控制癌症表型转化是T细胞疗法中瘤生长控制的关键. 将组织成像与多尺度建模相结合,为癌症治疗设计提供了新的见解.

关键词:
在T细胞,T细胞.基于代理的建模.细胞疗法是细胞疗法.组织成像数据的计算分析.免疫疗法 免疫疗法多重组织成像多重组织成像多尺度建模模型的使用.空间生物学空间生物学系统生物学 系统生物学瘤细胞表型 瘤细胞表型

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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