在手术后放射治疗的目标划定头癌在片重建后的头癌
Xuguang Scott Chen1, David J Sher2, Christopher Blake Sullivan3
1Department of Radiation Oncology, University of North Carolina, Chapel Hill, North Carolina.
Practical radiation oncology
|April 18, 2024
概括
在片重建后,将整个片纳入临床目标体积 (CTV) 进行头癌放射治疗是标准做法. 这种方法旨在防止边缘失误和内故障,优化治疗结果.
科学领域:
- 在瘤学瘤学.
- 辐射瘤学 辐射瘤学
- 头部和部手术 头部和部手术
背景情况:
- 在用片重建切除头癌之后,临床目标体积 (CTV) 划分具有挑战性.
- 一个关键的辩论涉及是否包括整个在CTV.
- 之前的研究表明,当板不完全包括在内时,就会发生边缘失误和板内部故障.
研究的目的:
- 评估在头癌患者的CTV中包括整个的标准实践.
- 讨论可能考虑将剂量减少到片部分的情景.
- 在具体情况下,提供案例简介,说明合理的折叠板节省.
主要方法:
- 对临床实践和现有病例系列的审查,涉及CTV划分后的翻盖重建.
- 分析与CTV.Flap包含/排除相关的结果.
- 病例简介与详细的临床情景的介绍.
主要成果:
- 在CTV中包括整个板是减轻复发风险的标准做法.
- 手术后的辐射可以改善片的结果 (脱毛,粘膜化,减少体积).
- 特定情况下,可能需要将剂量减少到远端片部分,以节省相邻的原生组织.
结论:
- 整个板通常包含在头癌放射治疗后重建的CTV中.
- 虽然一般包括在内,但在某些特定情况下,选择性减少剂量到远端片区域可能是合理的.
- 在剂量规划中,节省靠近片的未涉及本地组织是关键考虑因素.
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