根据月经周期阶段和口服避孕药的使用,食后食欲激素的差异变化:一项初步研究
Seth F McCarthy1, Logan K Townsend2, Greg L McKie1
1Department of Kinesiology and Physical Education, Wilfrid Laurier University, Waterloo, Ontario, Canada.
Appetite
|April 18, 2024
概括
口服避孕药和月经周期阶段稍微改变胃口激素,如 ghrelin 和 PYY. 在这项初步研究中,活跃的GLP-1和感知到的食欲没有受到影响.
科学领域:
- 内分泌学 在内分泌学.
- 人体生理学 人体生理学
- 营养科学 营养科学
背景情况:
- 食欲调节是复杂的,可以受到荷尔蒙波动的影响.
- 口服避孕药 (OCs) 含有合成激素,可能会影响代谢过程.
- 月经周期阶段涉及自然的荷尔蒙变化,可能会影响食欲控制.
研究的目的:
- 研究月经周期和口服避孕药对食欲调节的影响.
- 检查与食欲相关的荷尔蒙变化,包括酸格林,GLP-1和PYY.
- 为了比较自然骑自行车的女性和OC用户之间的食欲感知和荷尔蒙反应.
主要方法:
- 一项初步研究涉及10名自然循环女性 (非用户) 和9名口服避孕药用户 (用户).
- 参与者在三个月经阶段完成了实验性会议:卵泡 (FP),排卵 (OP) 和体 (LP).
- 采集了餐前和餐后的血液样本,以测量酸格林,活性GLP-1和总PYY;食欲感知也被记录下来.
主要成果:
- 对酸格林观察到三向相互作用 (组 x 阶段 x 时间),在OP和LP期间的USERS中,与非用户相比,USERS的度更高.
- 在OP期间的USERS中,酸格林的含量高于饭后的FP.
- 总PYY的三方相互作用显示,与特定时间点相比,FP和OP期间的USERS的度更高;对于GLP-1或食欲感知没有发现显著的影响.
结论:
- 月经周期阶段和口服避孕药的使用对酸格林和对食的总PYY反应产生轻微影响.
- 这些因素对活跃的GLP-1或主观食欲感知没有显著的影响.
- 需要对更大的样本进行进一步的研究,以证实这些关于食欲调节的初步发现.
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