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轻度肥胖不会影响妊娠载体周期的围产期结果

E Clain¹, L K Kaizer², M D Sammel^1,2

¹Department of Obstetrics and Gynecology, University of Colorado, Aurora, CO, USA.

Human reproduction (Oxford, England)

|April 18, 2024

概括

孕期载体体重指数 (BMI) 并没有显著影响良好的围产期结果. 然而,孕期携带者的更高的BMI与剖腹产和孕期大婴儿的增加率有关.

科学领域:

生殖医学和内分泌学.
孕产妇和胎儿医学孕产妇和胎儿医学
公共卫生和流行病学

背景情况:

妊娠载体 (GC) 的使用越来越多,这凸显了对最佳体重指数 (BMI) 需要明确指导方针的需要.
目前关于肥胖对孕产妇和胎儿健康状况的影响的数据有限.
肥胖女性自然或通过体外受精 (IVF) 怀孕面临更高的风险,但GC特定的数据很少.

研究的目的:

调查妊娠载体BMI和胚胎移植后的围产期结果之间的关联.
确定GC中的超重和肥胖是否会影响获得有利周产期结果的可能性.

主要方法:

从2015年1月到2020年12月,对1121个GC周期进行了回顾性队列研究.
排除接受联合IVF的同性伴侣.
主要结局:良好的围产期结局 (单独活产在≥37周,出生体重为2500-4000g). 二级结局包括活产率,临床怀孕,流产和分娩特征. 分析使用了一般化的线性模型,将BMI组与正常BMI进行比较.

主要成果:

在GCBMI和良好的产周结局,活产,临床怀孕或流产之间没有发现统计学上显著的关联.
在GC中,较高的BMI与活产婴儿中剖腹产 (P=0.015) 和妊娠年龄较大的婴儿 (P=0.023) 的增加率显著相关.
根据BMI组,人口统计和生殖史没有显著差异,尽管预期的父母年龄和冷/新鲜胚胎的使用有所不同.

结论:

在研究范围内的妊娠载体BMI似乎不会显著影响周产期良好结果的整体机会.
这项迄今为止规模最大的研究提供了证据,为GC选择和管理提供了指导.
需要进一步的研究来探索潜在的混因素,并完善对BMI在特定分娩结果中的作用的理解.

关键词:

这就是为什么BMI是BMI.怀孕的载体怀孕的载体肥胖肥胖肥胖肥胖肥胖肥胖肥胖肥胖体重过重的人超重.代孕母亲是什么意思

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