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一组分离子脂质用于系统mRNA向脏T细胞传递

Xinyue Zhang1, Kexin Su1, Shiqi Wu1,2

  • 1College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.

Angewandte Chemie (International ed. in English)
|April 18, 2024
PubMed
概括

研究人员开发了一种新型的一组分离离子化脂质,用于将向的信使RNA (mRNA) 输送到脏和T细胞. 这些简化的脂质纳米颗粒 (LNP) 为肝外mRNA免疫疗法应用提供了一个有前途的替代方案.

关键词:
阴性脂质 阴性脂质 阴性脂质提供mRNA的交付.一个组成部分的向量.脏T细胞向脏T细胞的目标

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