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Updated: Jun 28, 2025

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抗药物和肉毒神经毒素识别SV2A的结构基础

Atsushi Yamagata1, Kaori Ito2, Takehiro Suzuki3

  • 1Laboratory for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, Japan. atsushi.yamagata@riken.jp.

Nature communications
|April 18, 2024
PubMed
概括

结构洞察力揭示了抗药物 levetiracetam 和 brivaracetam 如何与突触囊泡糖蛋白2a (SV2A) 结合. 这种理解有助于设计新的治疗方法和神经成像剂.

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