确定与成人手握强度相关的特征和临床条件:项目基线健康研究
Kenneth A Taylor1,2, Megan K Carroll3, Sarah A Short4
1Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA. kenneth.taylor@duke.edu.
Scientific reports
|April 18, 2024
概括
手握强度 (HGS) 与各种健康因素有关,但这些联系因年龄和性别而异. 识别这些特定的关联可以改善不同人群的健康评估.
科学领域:
- 健康科学 卫生科学 卫生科学
- 生物统计学 生物统计学
- 老年学是指老年学的学科.
背景情况:
- 低手握强度 (HGS) 被认为是一种健康指标,主要在老年人中.
- 它的更广泛的临床意义和不同人口统计学方面的相关因素仍然不太了解.
研究的目的:
- 确定与HGS相关的关键因素.
- 将这些关联按年龄 (<65 vs. ≥65岁) 和性别分层.
主要方法:
- 利用了项目基线健康研究的2502名参与者的数据.
- 应用MI-LASSO与组方法来分析175个候选变量.
- 进行了性别和年龄特定的分析.
主要成果:
- 种族在不同的人口群体中显示出与HGS的不同关联.
- 骨质疏松症和骨质疏松症与女性的HGS有负面联系.
- 特定的免疫细胞计数 (中性粒细胞,单细胞,淋巴细胞) 在某些年龄和性别定义的群体中显示出与HGS的负相关性.
结论:
- HGS是各种临床特征的有价值指标.
- 与HGS相关的因素在很大程度上是特定于年龄和性别的.
- 研究结果强调了HGS作为健康指标的细微实用性.
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