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单细胞免疫谱的分析分析

Sergio E Irac1, Megan Sioe Fei Soon2, Nicholas Borcherding3,4

  • 1Cancer Immunoregulation and Immunotherapy, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

Nature methods
|April 18, 2024
PubMed
概括

分析单细胞T细胞和B细胞抗原受体测序数据为适应性免疫提供了深刻的见解. 本综述强调了计算机的进步,克服了解释复杂的免疫受体数据的挑战.

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Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
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