深膜呼吸训练对胃食道逆流引起的慢性咳的积极影响:一项临床随机对照研究
Shanshan Niu1,2, Tongyangzi Zhang1, Wanzhen Li1
1Department of Pulmonary and Critical Care Medicine, Tongji Hospital, School of Medicine, Tongji University, No. 389 Xincun Road, Shanghai, 200065, China.
深膜呼吸训练 (DEP) 在胃食道逆流引起的慢性咳 (GERC) 患者中显著改善了咳的解脱. 这种辅助疗法也提高了生活质量,减少了焦虑和抑郁症状.
科学领域:
- 肺部病理学 肺部病理学
- 胃肠病学 胃肠病学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 胃食道逆流引起的慢性咳 (GERC) 是一个重大的临床挑战.
- 目前的治疗方法往往不能完全缓解GERC患者的症状.
研究的目的:
- 为了评估深层隔膜呼吸训练 (DEP) 作为GERC的附加疗法的有效性.
- 评估DEP对咳症状,反流指标,心理困扰和隔膜肌肉活动的影响.
主要方法:
- 一个随机对照试验,涉及60名GERC患者,比较DEP训练加药与单药.
- 评估包括咳得分,反流问卷 (GerdQ),焦虑 (GAD-7),抑郁 (PHQ-9),睡眠质量 (PSQI) 和咳特定的生活质量 (LCQ).
- 在8周的干预之前和之后,还评估了素咳敏感性,B超声波和腹膜表面电肌图 (sEMG).
主要成果:
- 与对照组 (77%) 相比,DEP组实现了明显更高的咳解决率 (94%).
- 在DEP组中,与对照组相比,GerdQ,GAD-7,PSQI,LCQ和PHQ-9分数的显著改善.
- 在DEP组中,隔膜sEMG活性在治疗后的深呼吸和安静呼吸期间显著增加.
结论:
- 深层腹膜呼吸训练是一种有效的辅助治疗,用于控制胃食道逆流引起的慢性咳.
- 在GERC患者中,DEP可以改善咳解脱,反流症状,心理健康,睡眠质量和腹膜肌功能.
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