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Updated: Jun 28, 2025

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
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图书馆的大小在空间转录学数据中混了生物学

Dharmesh D Bhuva1,2,3, Chin Wee Tan4,5,6, Agus Salim4,7

  • 1South Australian immunoGENomics Cancer Institute (SAiGENCI), Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, 5005, Australia. dharmesh.bhuva@adelaide.edu.au.

Genome biology
|April 18, 2024
PubMed
概括

使用单细胞RNA测序方法规范空间分子数据可以扭曲组织结构分析. 研究人员应避免在疾病微环境研究中对图书馆大小进行校正,以准确地识别空间域.

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RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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