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Updated: Jun 18, 2026

An In Vitro Organ Culture Model of the Murine Intervertebral Disc
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在人类椎间盘细胞中的NFATc1/P2X7受体关系

Maria Pina Notarangelo1, Letizia Penolazzi1, Elisabetta Lambertini2

  • 1Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy.

Frontiers in cell and developmental biology
|April 19, 2024
PubMed
概括

椎间盘退化 (IDD) 与增加P2X7受体 (P2X7R) 表达相关. NFATc1和层A/C被确定为P2X7R的关键交互伙伴,为IDD提供了新的见解.

关键词:
转录因子NFATc1的转录因子在P2X7纯能受体中,P2X7纯能受体是缺氧诱导因子-1αα椎间盘细胞是椎间盘细胞.椎间盘退化 椎间盘退化层 A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C A/C近距离结合试验测试.

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