饮食质量与1型糖尿病患者血糖结果之间的关联
Melanie B Gillingham1, Martin Chase Marak2, Michael C Riddell3
1Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR, United States.
Current developments in nutrition
|April 19, 2024
概括
1型糖尿病患者的更高的饮食质量与更好的血糖控制和更低的胰岛素需求有关. 这种效果虽然是积极的,但与运动相比,效果不大.
科学领域:
- 内分泌学 在内分泌学.
- 营养科学 营养科学
- 代谢健康 代谢健康
背景情况:
- 饮食摄入量显著影响1型糖尿病 (T1DM) 患者的血糖反应和胰岛素需求.
- 饮食质量的日常变化会严重影响血糖水平和胰岛素管理.
研究的目的:
- 评估日常饮食质量对T1DM血糖控制的影响.
- 研究饮食质量与运动在治疗T1DM中的相互作用.
主要方法:
- 利用了1型糖尿病运动倡议 (T1DEXI) 的数据.
- 采用远程食品摄影方法对8天以上的饮食摄入量进行分析.
- 使用2015年健康饮食指数 (HEI) 量化饮食质量,并将日子分类为低 (≤57) 或高 (>57) HEI.
- 通过连续血糖监测 (CGM) 和使用配对t测试和强大的回归来分析血糖和每日胰岛素总剂量.
主要成果:
- 包括223名患有T1DM的成年人 (平均年龄37岁,HbA1c6.6%).
- 较高的HEI日 (平均66天) 与较低的HEI日 (平均47天) 相比显示出更好的血糖控制:在范围内的时间更长 (77.2%vs75.7%),在范围以上的时间更短 (19%vs21%),平均葡萄糖水平更低 (143vs145毫克/分升).
- 在高HEI日 (0.52U/kg/d) 和低HEI日 (0.54U/kg/d) 中,每日胰岛素总剂量较低.
结论:
- 较高的饮食质量,由增加的HEI得分表明,与改善的血糖控制和减少T1DM中的胰岛素需求有关.
- 饮食质量对血糖的影响在统计学上是显著的,但适度.
- 运动似乎对血糖控制的影响比饮食质量更大.
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