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Updated: Jun 28, 2025

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
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肝功能障碍对Trilaciclib药理动学的影响

Chao Li1, Richard A Preston2, Emily Dumas1

  • 1G1 Therapeutics, Inc., Research Triangle Park, North Carolina, USA.

Journal of clinical pharmacology
|April 19, 2024
PubMed
概括

在中度至重度肝功能障碍的患者中,trilaciclib的暴露增加. 建议对这些患者进行剂量降低,以确保安全性和有效性.

关键词:
这是一种CDK4/6抑制剂.孩子的Pugh 的肝功能受损 肝功能受损药物动力学 药物动力学小细胞肺癌是一种小细胞肺癌.三环结合物是什么意思

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